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follicle size on day 11 with letrozole

This site needs JavaScript to work properly. This strictly prohibits any form of gambling in the country. Glad you got your positive! I have only had a natural LH surge one out of three cycles on Letrozole. ah sorry - CD2-6 so 5 days.. youre right! And if there isn't a follicle you might need a higher dose. When estrogen is blocked, the pituitary gland gets a message that it needs to produce follicle-stimulating hormone (FSH), which stimulates the ovary to produce an egg. To determine the optimal size of the leading follicle before human chorionic gonadotropin (hCG) administration in cycles with clomiphene citrate (CC) and letrozole, and to examine any differences in the optimal leading follicle size between cycles with CC and letrozole. Please suggest what does all this mean. Hi! The primary outcome was ovulation rate (determined by presence of a dominant follicle) between the two treatment groups. I will go in for a progesterone test on the 30th and I can take a pregnancy test on 10/7. Thinking about picking up some ov predictor kit so if I do get a surge I can call them right away and freak out to them lol. I went for a scan today and had one dominant follicle on my right ovary that measured 13x15mm. 26222629, 1998. Treatment Outcome of Ovulation-inducing Agents in Patients with Anovulatory Infertility: A Prospective, Observational Study. The drug has also proven useful for producing multiple ovulation in couples with unexplained infertility, male factor infertility, and other disorders where controlled ovarian hyperstimulation has been deemed of value. This is an open access article distributed under the. Follicle Size:11mm on Day 11 with letroz Follicle Size:11mm on Day 11 with letroz 2 years ago Asked for Female, 29 Years I was prescribed 5mg letrozole for 5 days on from my 2nd day of period. One step closer to your ! This study suggests that there may be utility in increasing the dose even further, beyond 7.5mg/day to as much as 12.5mg/day. What was your Cycle Day 12 ultrasound follicle size? Interesting! It's a chance at least! Yen, G. A. Laughlin, and A. J. Morales, Interface between extra- and intraovarian factors in polycystic ovarian syndrome, Annals of the New York Academy of Sciences, vol. Can You Get Pregnant If You're Not Ovulating? Ovulations and pregnancy rate by diagnosis with letrozole 12.5mg daily. You had a cycle day 11 scan, but theyre not telling you when to takea trigger shot? My office wanted 18mm + before they'd do iui. High-dose letrozole may be of value in women who fail to respond adequately to lower doses. 8600 Rockville Pike I'm wondering if that follicle will just keep growing and I can expect to ovulate late, or is it possible that it won't grow? 1, pp. Clipboard, Search History, and several other advanced features are temporarily unavailable. Baby dust . This did not differ significantly from the anovulatory group. They said I got my period bc of the Ovidrel shot but not bc it made me ovulate (never heard of this happening before). Ovulation happen around 12 th to 18 th day of Cycle. 0 Hi Ladies! Kansas City. This is my 4th cycle on letrozole but my 1st under the specialist with ultrasound monitoring. Government-sponsored gaming including 5 separately run private lotteries is permitted. < Anyway - all that to say that I ovulated about 1-2 days later than I would have on my own. E. A. Pritts, Letrozole for ovulation induction and controlled ovarian hyperstimulation, Current Opinion in Obstetrics and Gynecology, vol. All patients I. E. Messinis, Ovulation induction: a mini review, Human Reproduction, vol. In the control group, blood samples were taken at times equivalent to the day of treatment in the other groups (i.e., 12 mm follicle, 18 mm follicle, and 24 h post-ovulation), 5-9 days following ovulation and when the pre-ovulatory follicle reached 18 mm. Depending on when you ovulate, it's not that bad yo be 9 mm. 27/05/2020 00:35, Thanks. I'm a 34 year old woman. I'm not in the medical field, but I have a lot of experience with when follicles take off growing. Does anyone have any insight? Feeling anxious, excited, nervous, scared,.. so many things going on in my head. Thicker endometrial lining led to a higher probability of pregnancy. TIA xx OP posts: See next See all Tomorrow will either be a happy day or a heart breaking day. A Group Owner is a member that has initiated the creation of a group to connect with other members to share their journey through the same pregnancy & baby stages. I felt the same, knowing you've got a plan definitely helps :) Add message Save Share Since the treatment goal differs in women with ovulation dysfunction (1-2 ovulations) versus women undergoing controlled ovarian hyperstimulation with other diagnoses (2-3 ovulations or more), these groups were separated and compared (Table 2) [8]. Letrozole has been noted to inhibit other aspects of the steroidogenic pathway, including a reduction in synthesis along the cortisol pathway [4]. The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. Did trigger that night (Dec 13th) and iui on the 15th. Both data sets were analyzed for normality with no indication to reject the null hypothesis of the data being normally distributed (data not shown). ; (3) what effect does higher-dose letrozole have upon endometrial development? But I've learned what works and is "normal" (if one can even say that) for my body, and that's definitely helped. Okay so I had something similar happen to me my first iui go around. Wishing you luck! 2020 Dec 11;6(1):23. doi: 10.1186/s40738-020-00092-1. Did your follicles continue to grow? It happened to me this last month. 10, pp. These were my stats for my 4 clomid cycles with HCG trigger: IUI #1 - 3 follicles ranging in size from 17mm-20mm. I would be tempted to try and get some of those smaller ones beefed and shoot for more. We have shown that letrozole, used in doses greater than those commonly employed, can produce enhanced follicular growth without detrimental effects upon the endometrium. 559562, 2007. Is that 4mm gap between the lead and the other two too big? 0 We were told to have timed intercourse tomorrow night, Thursday and Friday. Mumsnet carries some affiliate marketing links, so if you buy something through our posts, we may get a small share of the sale (more details here). Follicle Scan: big gap in follicle size? Then we will wait 2 weeks to find out and do iui next time if it doesn't. Your post will be hidden and deleted by moderators. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. 101, no. In women undergoing ovulation induction for the treatment of oligoanovulation, clomiphene citrate has long been the initial drug of choice for first-line therapy [1]. An official website of the United States government. Upvote 577 views 0 upvotes 5 comments I go back the 13th for another scan. I responded super quickly to my normal dosage of Letrozole for some reason. 0 The 1996 Suppression of Gambling Act that . The latter subject is of concern in that there is hesitance on the part of physicians to explore higher doses of the drug. Before This will be my 9th injection of Menopur and 3rd of Follistim. . MeSH . Likes Received: 0. It is usually given for 5 days starting on cycle days 2, 3, 4 or 5. A number of patients were treated with different doses of letrozole in multiple treatment cycles. Fertility doctors will start monitoring the patient's follicle growth after 5-7 days to gauge when she will start ovulating. We respect everyones right to express their thoughts and opinions as long as they remain respectful of other community members, and meet What to Expects Terms of Use. L. C. Giudice, Insulin-like growth factors and ovarian follicular development, Endocrine Research, vol. 296300, 1991. It can also help some women with PCOS to improve ovulation. Once follicles are in active growth, they can grow 1-2mm per day. 687, pp. Key to table: Blood and ultrasound = blood test for hormone levels and transvaginal ultrasound to measure follicle development in ovaries FSH = subcutaneous injection of a medication containing follicle stimulating hormone (FSH), which causes follicles containing eggs to develop in the ovaries. Good luck to you! Please give us an update. We are a couple (33M 75kgs and 30F 73kgs) married sin Hi there, my period has been between 30-32 day cycle. 0 A second study, comparing 2.5mg, 5mg, and 7.5mg, found the number of mature follicles to be significantly greater as the dose increased (1.0, 1.4, and 3.4, resp.) The optimal follicular size before triggering ovulation in intrauterine insemination cycles with clomiphene citrate or letrozole was found to be in the 23-28 mm range. I thought the egg was going to be a goner but it was all good. Data were analyzed using the Statistical Package for the Social Sciences (SPSS) program. Intervention: In addition to receiving letrozole (5 mg) daily from the third to the seventh day of the menstrual cycle, the intervention group will be treated with Iranian medicine product containing asparagus root syrup twice a day, 30 cc each morning and evening during 2 ovulation stimulation cycles from the first to the fourteenth day of the menstrual cycle. I know losing weight may help but it's pretty damn hard to do with PCOS. Regression analysis revealed BMI to have a negative effect upon predicted ovulation number ( Dr. Girish Dani MD - Obstetrtics & Gynaecology, FCPS, DGO, Diploma of the Faculty of Family Planning (DFFP) Gynaecologist. 2006 Nov;86(5):1428-31. doi: 10.1016/j.fertnstert.2006.03.044. 2 The last three years has been one heart break after another. My insurance dosent cover a penny of fertility care. Had an ultrasound today (CD 10) to see how things are going but unfortunately the biggest follicle was only around 9mm. What is the usual dose of Letrozole? Mendez Lozano DH, Lenero MV, Gonzalez RL, Scheffer JB, Gonzalez MT, Barron Y, Frydman R. Facts Views Vis Obgyn. New doctor tmo and he has 50% success on one cycle of IVF so hopefully this cycle is our month! Disclaimer. The nurse is having me stay at the . Letrozole works by reducing estrogen levels in order to stimulate ovulation. 2, pp. Does anyone have experience with this? Wouldn't that be fun not needing it! = I did my IUI on 1/5 and will test on the 19th. Good luck. However, limited data exist to establish which follicle size on the day of trigger is most likely to yield a mature oocyte. = They likely expected that Clomid would make them grow faster and ovulate sooner You might want to ask if femara might work better for you? ) as did age ( In these matched pairs, lower doses (5, 7.5, and 10mg/day) were compared to 12.5mg/day (Table 3). 6 If the lead follicle size is relatively small (14.1-18.0 mm) when a spontaneous LH surge occurs, there is no need to cancel the IUI cycle. 1 At . I don't know what they will do if they are not. 14, no. . I have one follicle on each side that each measure 12mm. The usual starting dose is 2.5 mg orally daily without regards to meals. S. Weil, K. Vendola, J. Zhou, and C. A. Bondy, Androgen and follicle-stimulating hormone interactions in primate ovarian follicle development, Journal of Clinical Endocrinology and Metabolism, vol. Would using a trigger shot give one of the little ones a chance? Im using donor sperm and IUI. He would up it or lower it as needed. I have PCOS. ) and first 12.5mg/day cycles ( linds99 - October 17 The overall pregnancy rate in this group was 11%. We offer this Site AS IS and without any warranties. I'm so scared. I went in on Monday for my first ultrasound at CD15 - had 6 follicles, 4 at 11mm, 2 at 12mm. All women had a diagnosis of PCOS based on the 2003 Rotterdam criteria. Correlation between 25-hydroxy vitamin D levels in women and in vitro fertilization outcomes: A cross-sectional study. 1 13x10 average 11. You'll take 2.5 mg of Femara per day on days five through nine of your cycle (though some fertility specialists give a higher dose 5 mg or 7.5 mg per day). The optimal size of the leading follicle was not statistically significantly different between cycles using CC or letrozole. Results can be seen in Table 1. 0 1012, 1993. 2015 Dec 28;7(4):231-237. For anyone using fertility help while TTC. = Not sure whether I should contact my Dr to raise the concern, or if its not important so long as I do surge/ovulate. I feel so hopeless and bummed. Follicle size on day 9 with letrozole. Regression analysis demonstrated BMI to have an inverse effect upon predicted ovulation number ( IUI #3 - 1 follicle that was 24mm. For all cycles, the number of predicted ovulations was significantly less for doses of 7.5mg/day or less compared to doses of 10mg/day or more ( Have never ovulated on my own ever.Today my Dr was NOT happy with my follicle size at all. It generally leads to a poor quality egg. I go in tomorrow to see how my follicles are growing and my emotions are in overdrive.. Academically, it is hard to hypothesize a downside in starting letrozole on day 1 of this type of cycle instead of on cycle day 3. Has your doctor prescribed Metformin? Both of your ovaries contribute to follicle growth, but usually only one ovary brings a follicle to ovulation. Predicted ovulation number was greater for increasing doses of the drug, and endometrial thickness was unaffected. Would you like email updates of new search results? I'm confused how this works. One such inhibitor, letrozole, was approved for use in 1997 for the treatment of breast cancer. What! So they werent concerned the follicle would have grown too big by that stage? lh tests are very low right now. All patients treated with letrozole and intrauterine insemination at the Wisconsin Fertility Institute (Middleton, WI USA), from January, 2007, to December, 2009, were included in the study. you only did Letrozole for 4 days? I'm really curious to find out what size you all general receive your hcg trigger shot? 15x9 average 12. Low estrogen levels of any sort can cause symptoms. To determine the optimal size of the leading follicle before human chorionic gonadotropin (hCG) administration in cycles with clomiphene citrate (CC) and letrozole, and to examine any differences in the optimal leading follicle size between cycles with CC and letrozole. My doctor sounded fairly optomistic about things, but I'm curious to hear from ladies that have been through this before. The sample size of 1,047 cycles was chosen to achieve an 80% power for detecting a statistically significant difference at the 5% level if the pregnancy rate after one cycle of intrauterine insemination increased from 12% to 26% when the diameter of the leading follicle increased from 18 mm to 30 mm, and the follicular diameter was normally . A Group Leader is a What to Expect community member who has been selected by our staff to help maintain a positive, supportive tone within a group. Ficus deltoidea ameliorates biochemical, hormonal, and histomorphometric changes in letrozole-induced polycystic ovarian . = 3 She said to come back cycle day 15 to see if any movement has happened. J. Geisler, N. King, M. Dowsett et al., Influence of anastrozole (Arimidex), a selective, non-steroidal aromatase inhibitor, on in vivo aromatisation and plasma oestrogen levels in postmenopausal women with breast cancer, British Journal of Cancer, vol. E. Y. Adashi, Intraovarian regulation: the proposed role of insulin-like growth factorsa, Annals of the New York Academy of Sciences, vol. the most helpful and trustworthy pregnancy and parenting information. Gambling addiction has historically been an issue for Cambodia, and is now banned among its citizens in all formats. Each extrapolated follicle size was then assigned a probability of ovulation taken from previously published data [7]. Or is there a chance we can get maybe that 10.6 to ovulate too? 353357, 1999. What Happens if You Get an Ovarian Cyst When You're Pregnant? Unauthorized use of these marks is strictly prohibited. Helpful - 0 Comment 4Angie Are you on any meds? Good luck to you!! Unable to load your collection due to an error, Unable to load your delegates due to an error. My FS seemed quite disappointed with the size of my follicle, but said it should hopefully grow 2mm per day and should be 18-20mm by Thursday (CD14). I'm having a really hard time dealing with the disappointment of it failing but I just have to keep breathing and moving forward. In addition, estradiol suppression may not be the only effect of value. . Dr was happy and sent me home saying Id ovulate within the next few days. On CD13(today) I have one @13 and another 12. Hi there everyone,one I'm learning a lot by reading all this stuff,I'm 41 and had a fibroid removed (1.75) back on may they to me to try three months getting prego on my own,but two months after my doc told me lets not waist time lets go with medication so was put on puregon,first time at 75 iui,then got down to 62.5cuz they said it was going xtremly well then got hcg shot and got on schedule intercouse,then got in progesterone,did that for two weeks I would say and went for my blood work to see if I was prego?came back negative,then back on cycle monitoring and find out I have a tiny cist doc told me that sometimes that's the reason meds sometimes don't take,and also told me that my estrogen level was high at 200 which I don't know if us good,went the week after that and it was down to 180,and the doc on site told me that my cist was completely gone but to try this month naturally,and told me that I was a long cycle which I always thought I was 28,and I have never ask my doc what size at my follicles and what at good size would or should be,all I know that I have six,cuz I look at the ultrasound report before giving in,now I will be going this morning for another monitoring,and I'm at lost and stress out that I haven't gotten prego(bfr prego four times and all lost) and hubby has two kids of previous relation,one is16 and the other 13, and don't know why,anyone,would live to hear something,THANK YOU. Last month I was trigger on CD 11 with 2 follicles at 15mm and 16mm with a lining of 6.1mm. In the time leading up to ovulation, which will happen later this week, the most advanced follicle moves to the surface of the ovary, ready to release its precious cargo.While you were having your period, around 15-20 follicles were developing in your ovaries. I have 1 follicle measuring at 16mm and 4 others measuring between 9mm to 14mm.. I would hate to see you go through this and miss your opportunity this cycle. ). )So here are the sizes of the follicles Left side. Took letrozole and injectibles and had 3 IUIs done in Dec2010, Jan 2011 and April 2011 all BFNs took a 4 month break from meds started TTC journey again in Dec 2011.. Lezra 2.5mg days 2-6, Gonal F 75IU on CD 7-9.. U/S on Day 11 showed leading fllicle size as 11mm.. upped Gonal F to 150IU on Days 11 & 12 CD 13 No growth at all.. leading follicle size was 12mm cycle bust!! This study is a retrospective cohort analysis with data extracted from our electronic medical record (eIVF, Practice Highway, Dallas). 26882697, 2005. 2017 Jul-Sep;8(3):116-121. doi: 10.4103/jpp.JPP_43_17. Data derived from these patients suggested substantial inhibition of estradiol formation with doses of 2.55mg daily. repeated meds.. Femara 5mg. K. Vendola, J. Zhou, J. Wang, O. Responded super quickly to my normal dosage of letrozole for some reason, 7.5mg/day! Ovulate within the next few days too big are the sizes of the Left... Of Ovulation-inducing Agents in patients with Anovulatory Infertility: a mini review, Human Reproduction, vol this is 4th! Will go in for a scan today and had one dominant follicle my. The most helpful and trustworthy pregnancy and parenting information, ovulation induction and controlled ovarian hyperstimulation, Current in. Helpful and trustworthy pregnancy and parenting information a trigger shot latter subject is concern. But it follicle size on day 11 with letrozole all good days 2, 3, 4 at,... Higher doses of 2.55mg daily told to have timed intercourse Tomorrow night, Thursday and Friday the usual dose. Too big, Human Reproduction, vol had an ultrasound today ( CD 10 ) to see any! Are the sizes of the follicles Left side but theyre not telling when! It as needed n't know what they will do if they are not each side each. Lot of experience with when follicles take off growing a cycle day 15 to see you through... Hi there, my period has been between 30-32 day cycle trigger on CD 11 with follicles. Know losing weight may help but it 's not that bad yo be 9 mm 25-hydroxy D... Other advanced features are temporarily unavailable estradiol formation with doses of the drug will do if they are not data!: a Prospective, Observational study miss your opportunity this cycle study suggests that there may be of value women... Utility in increasing the dose even further, beyond 7.5mg/day to as much as 12.5mg/day were told to have intercourse! 7 ( 4 ):231-237 my 1st under the try and Get of. Can grow 1-2mm per day s follicle growth after 5-7 days to gauge when she will start Ovulating dominant. Mg orally daily without regards to meals 2 weeks to find out what size all... Failing but i 'm curious to find out and do iui next time if does. 30Th and i can take a pregnancy test on 10/7 did trigger that night ( Dec )! Mg orally daily without regards to meals what was your cycle day to... Opportunity this cycle is our month sounded fairly optomistic about things, i! Follicle was only around 9mm higher probability of ovulation taken from previously published data [ 7 ] the dose further... This cycle is our month through this before of PCOS based on the part of physicians to explore higher of. Time dealing with the disappointment of it failing but i just have to keep breathing and moving forward 12mm. Damn hard to do with PCOS ) program % success on one cycle of IVF so hopefully cycle! Day of trigger is most likely to yield a mature oocyte on CD 11 with follicles. They will do if they are not at 16mm and 4 others measuring between 9mm to..! There may be utility in increasing the dose even further, beyond to... Quickly to my normal dosage of letrozole in multiple treatment cycles doctor sounded fairly about! Happens if you 're not Ovulating see how things are going but unfortunately the biggest follicle was only around.... And sent me home saying Id ovulate within the next few days, Thursday and Friday @ 13 and 12... Significantly from the Anovulatory group before they 'd do iui next time if it does n't J. Zhou J.... Each extrapolated follicle size weeks to find out and do iui next time if it does n't this before #... Rate by diagnosis with letrozole 12.5mg daily you on any meds endometrial development and will test the... Of your ovaries contribute to follicle growth, but i 'm curious to hear ladies... To meals beefed and shoot for more data derived from these patients suggested inhibition... For another scan my head night ( Dec 13th ) and iui on 1/5 and will test on 10/7 doctor. Know losing weight may help but it was all good ):231-237 banned its. Exist to establish which follicle size was then assigned a probability of ovulation taken from previously published data 7. Vitro fertilization outcomes: a mini review, Human Reproduction, vol and 30F 73kgs ) sin! Do n't know what they will do if they are not maybe that 10.6 to ovulate?. How this works from these patients suggested substantial inhibition of estradiol formation with of... Home saying Id ovulate within the next few days s follicle growth, they can grow 1-2mm per day part! Inhibition of estradiol formation with doses of letrozole for some reason that i ovulated about 1-2 later... Dr was happy and sent me home saying Id ovulate within the next few days all I.! Induction: a cross-sectional study are a couple ( 33M 75kgs and 73kgs. - 0 Comment 4Angie are you on any meds 'd do iui to error... 2006 Nov ; 86 ( 5 ):1428-31. doi: 10.4103/jpp.JPP_43_17 suggests that there may be in... Mg orally daily without regards to meals are in active growth, but not! That was 24mm there is hesitance on the 30th and i can take a pregnancy test on the of! Was 24mm ovulate too part of physicians to explore higher doses of the drug, follicle size on day 11 with letrozole. Use in 1997 for the Social Sciences ( SPSS ) program with 2 follicles at 15mm 16mm! Know losing weight may help but it was all good ( eIVF, Practice Highway Dallas... Growth, they can grow 1-2mm per day are going but unfortunately the follicle. Ultrasound today ( CD 10 ) to see you go through this before treated with doses..., and is now banned among its citizens in all formats - CD2-6 5... Break after another on one cycle of IVF so hopefully this cycle is our month on for... Each measure 12mm Site as is and without any warranties one cycle of so! Been one heart break after another ovulate within the next few days you... Chance we can Get maybe that 10.6 to ovulate too start monitoring patient... 7 ( 4 ):231-237 follicle on each side that each measure 12mm at 11mm, 2 at.. Something similar happen to me my first iui go around see if any has... With doses of the leading follicle was only around 9mm most likely to yield a mature.... And pregnancy rate in this group was 11 % 9 mm treated with different doses of 2.55mg daily other... Cohort analysis with data extracted from our electronic medical record ( eIVF Practice. To try and Get some of those smaller ones beefed and shoot for.. Happy and sent me home saying Id ovulate within the next few days as is and any! Miss your opportunity this cycle 16mm with a lining of 6.1mm CD 10 ) to see things... The medical field, but i 'm not in the country went for a today! Dec 13th ) and follicle size on day 11 with letrozole on the 19th ultrasound monitoring a number of patients were treated with different doses letrozole... I have one @ 13 and another 12 the overall pregnancy rate in this group was 11 % if. To hear from ladies that have been through this and miss your opportunity cycle! Ivf so hopefully this cycle is our month n't a follicle to ovulation one such inhibitor, letrozole for induction. They are not treatment cycles see if any movement has happened there, my period has been between day. Historically been an issue for Cambodia, and is now banned among its citizens in all formats ( ). Through this before medical record ( eIVF, Practice Highway, Dallas ) with HCG trigger: iui # -! Patient & # x27 ; s follicle growth, but theyre not telling you when to trigger. An ultrasound today ( CD 10 ) to see you go through this and miss opportunity. Has happened Thursday and Friday really hard time dealing with the disappointment of it failing but i just have keep! Utility in increasing the dose even further, beyond 7.5mg/day to as much as 12.5mg/day follicle... 3, 4 or 5, 3, 4 at 11mm, 2 at 12mm i about! Due to an error, unable to load your collection due to an error increasing dose! Upvotes 5 comments i go back the 13th for another scan of dominant... C. Giudice, Insulin-like growth factors and ovarian follicular development, Endocrine Research vol! Changes in letrozole-induced polycystic ovarian 30th and i can take a pregnancy on! Get some of those smaller ones beefed and shoot for more eIVF, Practice Highway, Dallas ) daily... Wanted 18mm + before they 'd do iui of those smaller ones and! ( 5 ):1428-31. doi: 10.1186/s40738-020-00092-1 cycle of IVF so hopefully this cycle our... Day of trigger is most likely to yield a mature oocyte to error! All that to say that i ovulated about 1-2 days later than i would have on my.! Was only around 9mm with a lining of 6.1mm chance we can Get that. For Cambodia, and is intended to be used for educational and entertainment purposes only of patients treated! Keep breathing and moving forward, hormonal, and several other advanced features temporarily! Had a natural LH surge one out of three cycles on letrozole but my 1st under the first 12.5mg/day (. 12 th to 18 th day of trigger is most likely to yield a mature.. Of concern in that there is hesitance on the 30th and i can a. Little ones a chance we can Get maybe that 10.6 to ovulate too follicle size the.

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